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There aren't any scientific tests on placental transfer or teratogenicity of the combination of ergotamine and caffeine
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nirmatrelvir/ritonavir will boost the stage or outcome of ergotamine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
itraconazole will increase the stage or result of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Enhanced danger of ergotism bringing about cerebral ischemia and/or ischemia of the extremities
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miconazole vaginal will enhance the stage or outcome of ergotamine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
bremelanotide will minimize the level or outcome of ergotamine by Other (see comment). Avoid or Use Alternate Drug. Bremelanotide may possibly slow gastric emptying and potentially lessens the rate and extent of absorption of concomitantly administered oral medications.
as an alternative to proceeding by rulemaking when temporarily scheduling substances. On condition that Congress exclusively demands the Administrator (as delegated with the Legal professional Typical) to abide by rulemaking strategies for other
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ciprofloxacin will enhance the degree or result of caffeine by impacting hepatic enzyme CYP1A2 metabolism. Use Warning/Keep track of. The hepatic metabolism of caffeine could be lowered by ciprofloxacin; pharmacologic consequences of caffeine may be increased.
The rising usage of novel designer BZD derivatives continues to be just lately noted in international locations, wherever these chemical compounds would not have promoting authorization as medicinal products and solutions (two).
ceritinib increases levels of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Steer clear of concurrent use of CYP3A substrates recognized read more to obtain slender therapeutic indices or substrates principally metabolized by CYP3A through treatment method with ceritinib; if use of those drugs is unavoidable, contemplate dose reduction.